Drugs taken for enhanced liver enzyme secretion have adverse effects on the birth control pills. Anti tuberculosis drugs and anti fungal drugs have also negative affinity towards these pills. In some cases, prescriptions of dentists and dermatologists also hinder the effectiveness of birth control pills. Antibiotics have the least compatibility towards these pills. Antibiotics coming under this section are Rifampin, penicillin, Amoxicillin, Sulfonamide, Griseofulvin, Minocycline and Phenobarbital etc.

 Anti-HIV Protease Inhibitors like Ritonavir can also decrease the efficiency of birth control pills. If you are taking antidepressants like Nefazodone, these pills might not deliver the desired result.  Diabetic women with medications like Troglitazone and Pioglitazone might not avail the full benefit of consuming birth control pills. However, the degree of ineffectiveness varies from drug to drug. It depends upon specific drugs capacity to disorder hormonal balance required for birth control.  If you are advised to take one or more of the above drugs, consulting your doctor before beginning with these pills is advisable. The doctor will analyze the side effects of drug-drug reaction and prescribe further medications accordingly.